A nurse is teaching a newly licensed nurse about adverse effects of medications.
The nurse should include that which of the following medications can cause constipation?
Anticholinergics/antispasmodics.
Opioid narcotics.
Iron supplements.
Magnesium-containing antacids.
Correct Answer : A,B,C
Choice A rationale
Anticholinergics/antispasmodics can cause constipation by reducing the muscle contractions of the gastrointestinal tract, leading to slower movement of contents and resulting in constipation.
Choice B rationale
Opioid narcotics cause constipation by binding to opioid receptors in the gastrointestinal tract, which decreases intestinal motility and inhibits the secretion of fluids, leading to hard and dry stools.
Choice C rationale
Iron supplements can cause constipation as a common side effect due to their effect on the gastrointestinal tract. They can make stools harder and more difficult to pass.
Choice D rationale
Magnesium-containing antacids typically do not cause constipation. In fact, they are more likely to have a laxative effect due to the presence of magnesium, which can increase water in the intestines and soften stools.
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Correct Answer is C
Explanation
Choice A rationale
Toxic levels refer to concentrations of a medication that are high enough to cause harmful effects or poisoning. This is not related to the lowest serum concentration.
Choice B rationale
Peak levels are the highest concentration of a medication in the bloodstream after administration. This occurs after the drug is absorbed and distributed.
Choice C rationale
Trough levels occur when the medication is at its lowest concentration in the bloodstream, typically just before the next dose is due. Monitoring trough levels helps ensure therapeutic effectiveness while avoiding toxicity.
Choice D rationale
Half-life refers to the time it takes for the concentration of a drug in the bloodstream to decrease by half. It is not directly related to the lowest serum concentration at a specific point in time.
Correct Answer is D
Explanation
Choice A rationale
Hypothermia is not commonly associated with diarrhea. Diarrhea typically leads to fluid loss and dehydration rather than changes in body temperature.
Choice B rationale
A rigid abdomen is not a typical finding for diarrhea. It may indicate other gastrointestinal issues, such as peritonitis, rather than dehydration caused by diarrhea.
Choice C rationale
Decreased bowel sounds are not typically expected with diarrhea, which often presents with increased bowel sounds due to increased motility.
Choice D rationale
Dehydration is a common finding in clients with diarrhea due to the excessive loss of fluids and electrolytes from frequent, loose stools. It can lead to symptoms such as dry mouth, reduced urine output, and dizziness.