A nurse is teaching a class about pharmacodynamics.
The nurse should include that which of the following medication levels occurs when a medication is at the lowest serum concentration?
Toxic.
Peak.
Trough.
Half-life.
The Correct Answer is C
Choice A rationale
Toxic levels refer to concentrations of a medication that are high enough to cause harmful effects or poisoning. This is not related to the lowest serum concentration.
Choice B rationale
Peak levels are the highest concentration of a medication in the bloodstream after administration. This occurs after the drug is absorbed and distributed.
Choice C rationale
Trough levels occur when the medication is at its lowest concentration in the bloodstream, typically just before the next dose is due. Monitoring trough levels helps ensure therapeutic effectiveness while avoiding toxicity.
Choice D rationale
Half-life refers to the time it takes for the concentration of a drug in the bloodstream to decrease by half. It is not directly related to the lowest serum concentration at a specific point in time.
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Correct Answer is D
Explanation
Choice D rationale
Dark-colored urine is a common indicator of dehydration. When the body is dehydrated, urine becomes more concentrated, leading to darker color due to higher levels of waste products.
Choice A rationale
Cloudy urine is not typically associated with dehydration. It may indicate the presence of an infection, inflammation, or other medical conditions.
Choice B rationale
Urine osmolality of 200 mOsm/kg suggests diluted urine, which is contrary to the expectation in dehydration. Dehydration would typically result in higher urine osmolality as the kidneys conserve water.
Choice C rationale
Urine specific gravity of 1.015 falls within the normal range (1.005 to 1.030). In dehydration, specific gravity would be expected to be higher as the urine becomes more concentrated to conserve water.
Correct Answer is D
Explanation
Choice A rationale
A sigmoid colostomy usually produces stool that is more formed compared to an ileostomy. This is because the colostomy is created from the sigmoid colon, where water absorption occurs.
Choice B rationale
The stoma should not be painful after the procedure. Pain may indicate complications, and the stoma itself lacks nerve endings.
Choice C rationale
The stoma should be a bright red or pink color, indicating good blood supply. A purple color could suggest ischemia or poor blood flow.
Choice D rationale
A sigmoid colostomy is typically located in the left lower abdomen because the sigmoid colon is situated in this area of the body.