A nurse is teaching a class about pharmacodynamics.
The nurse should include that which of the following medication levels occurs when a medication is at the lowest serum concentration?
Toxic.
Peak.
Trough.
Half-life.
The Correct Answer is C
Choice A rationale
Toxic levels refer to concentrations of a medication that are high enough to cause harmful effects or poisoning. This is not related to the lowest serum concentration.
Choice B rationale
Peak levels are the highest concentration of a medication in the bloodstream after administration. This occurs after the drug is absorbed and distributed.
Choice C rationale
Trough levels occur when the medication is at its lowest concentration in the bloodstream, typically just before the next dose is due. Monitoring trough levels helps ensure therapeutic effectiveness while avoiding toxicity.
Choice D rationale
Half-life refers to the time it takes for the concentration of a drug in the bloodstream to decrease by half. It is not directly related to the lowest serum concentration at a specific point in time.
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View Related questions
Correct Answer is D
Explanation
Choice A rationale
Blood in the urine (hematuria) is not a typical finding in urinary retention. It may indicate other conditions such as infection, stones, or malignancy.
Choice B rationale
Cloudy urine is often a sign of infection, not typically associated with urinary retention. It can be caused by the presence of bacteria, white blood cells, or crystals.
Choice C rationale
Dark-colored urine can result from dehydration or certain foods and medications. It is not a specific finding of urinary retention.
Choice D rationale
Leakage of urine, also known as overflow incontinence, can occur in urinary retention. This happens when the bladder becomes overly full, and small amounts of urine leak out due to the pressure.
Correct Answer is A
Explanation
Choice A rationale
Colonoscopy is the recommended test for screening for rectal cancer. It allows for direct visualization of the entire colon and rectum, enabling the detection and biopsy of polyps or
suspicious lesions. It is the gold standard for colorectal cancer screening.
Choice B rationale
Endoscopic retrograde cholangiopancreatography (ERCP) is used to diagnose and treat conditions of the bile ducts, pancreas, and gallbladder. It’s not typically used for colorectal
cancer screening.
Choice C rationale
An upper GI series involves X-rays of the upper gastrointestinal tract (esophagus, stomach, and duodenum) after swallowing a contrast medium. This test does not visualize the
lower GI tract, including the colon and rectum, and is therefore not suitable for rectal cancer screening.
Choice D rationale
Upper GI endoscopy allows for direct visualization of the upper gastrointestinal tract but does not reach the colon and rectum. Hence, it is not used for screening rectal cancer