A nurse is teaching a class about pharmacodynamics.
The nurse should include that which of the following medication levels occurs when a medication is at the lowest serum concentration?
Toxic.
Peak.
Trough.
Half-life.
The Correct Answer is C
Choice A rationale
Toxic levels refer to concentrations of a medication that are high enough to cause harmful effects or poisoning. This is not related to the lowest serum concentration.
Choice B rationale
Peak levels are the highest concentration of a medication in the bloodstream after administration. This occurs after the drug is absorbed and distributed.
Choice C rationale
Trough levels occur when the medication is at its lowest concentration in the bloodstream, typically just before the next dose is due. Monitoring trough levels helps ensure therapeutic effectiveness while avoiding toxicity.
Choice D rationale
Half-life refers to the time it takes for the concentration of a drug in the bloodstream to decrease by half. It is not directly related to the lowest serum concentration at a specific point in time.
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Correct Answer is C
Explanation
Choice A rationale
Including toilet paper with the collected urine can contaminate the sample and affect the accuracy of the test results.
Choice B rationale
The first void at the start of the collection period should be discarded to ensure that only urine produced during the 24-hour period is collected.
Choice C rationale
Refrigerating the urine during the collection period helps preserve the sample and prevent bacterial growth, which could alter the test results.
Choice D rationale
The last void at the end of the collection period should be included to ensure that the full 24-hour period is accounted for in the collection.
Correct Answer is D
Explanation
Choice A rationale
Collecting two stool specimens from the same area of the stool is incorrect because specimens should be taken from different areas to ensure a representative sample of the stool for testing.
Choice B rationale
Using toilet paper to transfer the stool specimen is not recommended as it can contaminate the sample and interfere with test results.
Choice C rationale
Applying four drops of developing solution to each stool specimen is incorrect. The usual procedure involves applying a specific number of drops as indicated by the test instructions, which may vary.
Choice D rationale
Waiting 30 seconds after applying the developing solution is correct. This waiting period allows the test to react and provide accurate results for the presence of occult blood.