A nurse is teaching a class about pharmacodynamics.
The nurse should include that which of the following medication levels occurs when a medication is at the lowest serum concentration?
Toxic.
Peak.
Trough.
Half-life.
The Correct Answer is C
Choice A rationale
Toxic levels refer to concentrations of a medication that are high enough to cause harmful effects or poisoning. This is not related to the lowest serum concentration.
Choice B rationale
Peak levels are the highest concentration of a medication in the bloodstream after administration. This occurs after the drug is absorbed and distributed.
Choice C rationale
Trough levels occur when the medication is at its lowest concentration in the bloodstream, typically just before the next dose is due. Monitoring trough levels helps ensure therapeutic effectiveness while avoiding toxicity.
Choice D rationale
Half-life refers to the time it takes for the concentration of a drug in the bloodstream to decrease by half. It is not directly related to the lowest serum concentration at a specific point in time.
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Correct Answer is D
Explanation
Choice A rationale
Collecting two stool specimens from the same area of the stool is incorrect because specimens should be taken from different areas to ensure a representative sample of the stool for testing.
Choice B rationale
Using toilet paper to transfer the stool specimen is not recommended as it can contaminate the sample and interfere with test results.
Choice C rationale
Applying four drops of developing solution to each stool specimen is incorrect. The usual procedure involves applying a specific number of drops as indicated by the test instructions, which may vary.
Choice D rationale
Waiting 30 seconds after applying the developing solution is correct. This waiting period allows the test to react and provide accurate results for the presence of occult blood.
Correct Answer is B
Explanation
Choice A rationale
Aluminum-containing antacids often cause constipation due to their effect on bowel motility, not diarrhea. They work by neutralizing stomach acid but can lead to decreased bowel movements.
Choice B rationale
Magnesium-containing antacids can cause diarrhea as a side effect. They work by neutralizing stomach acid, and the excess magnesium in the intestines can cause loose stools or diarrhea.
Choice C rationale
Antibiotics can cause diarrhea by disrupting the balance of normal gut bacteria. This disruption can lead to overgrowth of harmful bacteria, such as Clostridium difficile, which can cause diarrhea.
Choice D rationale
Anticholinergics/antispasmodics typically cause constipation rather than diarrhea. They inhibit the parasympathetic nervous system, which slows down gut motility.
Choice E rationale
Opioid narcotics can cause constipation because they slow down the movement of the intestines. They do this by binding to opioid receptors in the gut, which decreases peristalsis.