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A nurse is teaching a class about pharmacodynamics.
The nurse should include that which of the following medication levels occurs when a medication is at the lowest serum concentration?

A.

Toxic.

B.

Peak.

C.

Trough.

D.

Half-life.

Answer and Explanation

The Correct Answer is C

Choice A rationale

Toxic levels refer to concentrations of a medication that are high enough to cause harmful effects or poisoning. This is not related to the lowest serum concentration.

 

Choice B rationale

Peak levels are the highest concentration of a medication in the bloodstream after administration. This occurs after the drug is absorbed and distributed.

 

Choice C rationale

Trough levels occur when the medication is at its lowest concentration in the bloodstream, typically just before the next dose is due. Monitoring trough levels helps ensure therapeutic effectiveness while avoiding toxicity.

 

Choice D rationale

Half-life refers to the time it takes for the concentration of a drug in the bloodstream to decrease by half. It is not directly related to the lowest serum concentration at a specific point in time.


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View Related questions

Correct Answer is D

Explanation

Choice D rationale

Intravenous (IV) administration has the fastest rate of absorption because the medication is delivered directly into the bloodstream, bypassing the absorption barriers of the digestive

system or muscle tissue. This ensures rapid onset of action.

Choice A rationale

Enteral administration involves the gastrointestinal tract, including oral and feeding tube methods. Absorption is slower as the medication passes through the digestive system before

entering the bloodstream.

Choice B rationale

Intramuscular (IM) administration involves injecting the medication into muscle tissue, where it is absorbed into the bloodstream. Absorption is quicker than enteral routes but slower

compared to IV administration.

Choice C rationale

Topical administration involves applying medication to the skin or mucous membranes. Absorption is generally slower and is intended for local or systemic effects, depending on the medication.

Correct Answer is D

Explanation

Choice A rationale

Blood in the urine (hematuria) is not a typical finding in urinary retention. It may indicate other conditions such as infection, stones, or malignancy.

Choice B rationale

Cloudy urine is often a sign of infection, not typically associated with urinary retention. It can be caused by the presence of bacteria, white blood cells, or crystals.

Choice C rationale

Dark-colored urine can result from dehydration or certain foods and medications. It is not a specific finding of urinary retention.

Choice D rationale

Leakage of urine, also known as overflow incontinence, can occur in urinary retention. This happens when the bladder becomes overly full, and small amounts of urine leak out due to the pressure.

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