A nurse is completing the medical reconciliation on an elderly client taking several medications. Which of the following prescribed medications places this client at risk for orthostatic hypotension? (Select all that apply.)
furosemide
Simvastatin
Losartan
Nifedipine
Clopidogrel
Correct Answer : A,C,D
A) Furosemide: This is a loop diuretic that can lead to dehydration and electrolyte imbalances, both of which can contribute to orthostatic hypotension. The medication's diuretic effect can cause a significant drop in blood volume, increasing the risk of low blood pressure upon standing.
B) Simvastatin: This medication is used to lower cholesterol levels and is not associated with orthostatic hypotension. It does not have a direct impact on blood pressure or volume.
C) Losartan: As an angiotensin II receptor blocker (ARB), losartan is used to treat hypertension. It can cause vasodilation and may lead to orthostatic hypotension, particularly in elderly clients or those who are volume-depleted.
D) Nifedipine: This calcium channel blocker is used to treat hypertension and can cause vasodilation. It may lead to orthostatic hypotension as well, especially during dose adjustments or if the client is dehydrated.
E) Clopidogrel: This antiplatelet medication is used to prevent blood clots and does not directly cause orthostatic hypotension. Its primary action is to inhibit platelet aggregation, not to affect blood pressure.
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Correct Answer is C
Explanation
A) Increase of high-density lipoproteins: While higher levels of high-density lipoproteins (HDL) are generally associated with a lower risk of cardiovascular disease, enalapril is not primarily used to target lipid levels. Its main purpose is to manage blood pressure and reduce the risk of heart failure and renal complications, rather than specifically affecting HDL levels.
B) Decreased pain from intermittent claudication: Intermittent claudication is typically related to peripheral artery disease, which may not be directly improved by enalapril. While managing blood pressure can indirectly benefit circulation, enalapril is not indicated specifically for alleviating pain associated with claudication.
C) Decreased blood pressure: Enalapril is an ACE inhibitor used primarily to treat hypertension. A significant decrease in blood pressure is a direct therapeutic effect of the medication, indicating that it is effectively managing the client’s condition. Monitoring blood pressure helps assess the medication's efficacy in achieving the desired therapeutic outcome.
D) Decrease in low-density lipoproteins: Although reducing low-density lipoprotein (LDL) levels can benefit cardiovascular health, enalapril is not primarily prescribed for this purpose. Its effects on lipid levels are minimal compared to its role in lowering blood pressure and protecting renal function, making a decrease in LDL levels an irrelevant indicator of its therapeutic effect.
Correct Answer is C
Explanation
A) Ambulating soon after surgery: Early ambulation is encouraged for postoperative clients to promote circulation and reduce the risk of venous thromboembolism (VTE). Mobilizing helps prevent stasis of blood in the veins, making this an appropriate action rather than an unsafe one.
B) Flexing her ankles: Ankle flexion exercises can help improve venous return and circulation in the lower extremities. This action is generally recommended to prevent VTE, making it a safe and beneficial practice for postoperative clients.
C) Massaging her legs: Massaging the legs is considered unsafe for a client at risk for VTE. This action can dislodge a thrombus (blood clot) if one is present, leading to potential complications such as pulmonary embolism. Therefore, the nurse should instruct the client to avoid leg massages.
D) Elevating her feet: Elevating the feet is a recommended practice to promote venous return and reduce swelling in postoperative clients. This action can help prevent VTE and is generally considered safe and beneficial.