A nurse is caring for a client who has hypertension and nephropathy due to type 2 diabetes mellitus. The nurse should expect to administer which of the following medications to slow the progression of the nephropathy?
Sitagliptin.
Glipizide.
Metoprolol.
Losartan.
The Correct Answer is D
Choice A rationale
Sitagliptin is a DPP-4 inhibitor used to manage blood sugar levels in type 2 diabetes but does not specifically slow the progression of nephropathy.
Choice B rationale
Glipizide is a sulfonylurea that helps control blood sugar levels but does not have a direct effect on slowing nephropathy progression.
Choice C rationale
Metoprolol is a beta-blocker used to manage hypertension but does not specifically target nephropathy progression.
Choice D rationale
Losartan is an angiotensin II receptor blocker (ARB) that helps manage hypertension and has been shown to slow the progression of nephropathy in patients with type 2 diabetes.
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Correct Answer is D
Explanation
Choice A rationale
CBC results are not directly related to the initiation of alendronate therapy.
Choice B rationale
Family history of colon cancer is not relevant to alendronate therapy.
Choice C rationale
Thyroid function is not directly related to alendronate therapy.
Choice D rationale
Pregnancy status should be assessed as alendronate is contraindicated during pregnancy.
Correct Answer is B
Explanation
Choice A rationale
Crushing tadalafil is not recommended as it can alter the medication’s effectiveness and absorption. Tadalafil should be taken whole to ensure proper dosage and efficacy.
Choice B rationale
Tadalafil can decrease blood pressure by relaxing blood vessels, which allows for increased blood flow. This is a known effect of phosphodiesterase type 5 (PDE5) inhibitors like tadalafil.
Choice C rationale
Tadalafil should not be taken more than once a day. Taking it twice a day can increase the risk of side effects and is not recommended.
Choice D rationale
The effects of tadalafil can last up to 36 hours, not just 4 hours. This prolonged duration is one of the reasons it is preferred by some patients.