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A nurse is caring for a client who has hypertension and nephropathy due to type 2 diabetes mellitus. The nurse should expect to administer which of the following medications to slow the progression of the nephropathy?

A.

Sitagliptin.

B.

Glipizide.

C.

Metoprolol.

D.

Losartan.

Answer and Explanation

The Correct Answer is D

Choice A rationale

 

Sitagliptin is a DPP-4 inhibitor used to manage blood sugar levels in type 2 diabetes but does not specifically slow the progression of nephropathy.

 

Choice B rationale

 

Glipizide is a sulfonylurea that helps control blood sugar levels but does not have a direct effect on slowing nephropathy progression.

 

Choice C rationale

 

Metoprolol is a beta-blocker used to manage hypertension but does not specifically target nephropathy progression.

 

Choice D rationale

 

Losartan is an angiotensin II receptor blocker (ARB) that helps manage hypertension and has been shown to slow the progression of nephropathy in patients with type 2 diabetes.


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View Related questions

Correct Answer is E

Explanation

Choice A rationale

Hypercalcemia is not typically a risk in the emergency department unless the patient has a specific condition that causes elevated calcium levels.

Choice B rationale

Hypotension can occur in the emergency department, especially in cases of shock or severe dehydration, but it is not the most common risk.

Choice C rationale

Hypokalemia can occur, particularly in patients with certain medical conditions or those taking diuretics, but it is not the most common risk.

Choice D rationale

Hypernatremia can occur, especially in patients with dehydration or certain medical conditions, but it is not the most common risk.

Choice E rationale

Hypoglycemia is a common risk in the emergency department, especially in patients with diabetes or those who have not eaten for an extended period.

Correct Answer is A

Explanation

Choice A rationale

Naloxone is an opioid antagonist that rapidly reverses the effects of opioid overdose, including respiratory depression. It binds to opioid receptors and displaces the opioid molecules, reversing their effects.

Choice B rationale

Bisacodyl is a stimulant laxative used to treat constipation. It does not have any effect on opioid-induced respiratory depression.

Choice C rationale

Flumazenil is a benzodiazepine antagonist used to reverse the effects of benzodiazepines, not opioids. It is not effective in treating opioid-induced respiratory depression.

Choice D rationale

Pentazocine is an opioid agonist-antagonist used for pain relief. It does not reverse opioid-induced respiratory depression and can potentially worsen the condition.

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