A nurse is caring for a client who has HIV and a CD4-T-cell count of 150/mm³. Which of the following conditions should the nurse monitor the client for?
Hepatitis
Tuberculosis
Gonorrhea
Chlamydia
The Correct Answer is B
A. Hepatitis is a concern for individuals with HIV, but it is not specifically indicated by a low CD4-T-cell count.
B. A CD4-T-cell count of 150/mm³ indicates severe immunosuppression, making the client highly susceptible to opportunistic infections like tuberculosis, which is common in individuals with HIV.
C. While gonorrhea is a risk for sexually active individuals, it is not specifically related to the low CD4-T-cell count.
D. Chlamydia is also a sexually transmitted infection, but similar to gonorrhea, it is not directly linked to the immunocompromised state indicated by the CD4-T-cell count.
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Correct Answer is B
Explanation
A. In the assembly stage, other proteins and enzymes are involved in the packaging of viral components into new virions, not integrase.
B. During the integration stage, integrase is essential as it inserts the newly formed viral DNA into the host's genome, enabling the virus to utilize the host's cellular machinery for replication.
C. Integrase does not participate in the entry stage; this stage is facilitated by other proteins that aid in the fusion of the virus with the host cell membrane.
D. Integrase is not involved in reverse transcription; that process is facilitated by the enzyme reverse transcriptase, which converts viral RNA into DNA.
Correct Answer is C
Explanation
A. While knowing the location of the assault may be relevant for police reports, it does not directly pertain to the client’s health and potential exposure to HIV.
B. Permission to contact the police is important for legal reasons, but the priority is to address the client's health needs first.
C. Identifying the individual who assaulted the client is critical for assessing the risk of HIV exposure and determining the need for post-exposure prophylaxis (PEP). This question directly impacts the client’s immediate health care.
D. Understanding the day and time of the assault is useful for legal documentation but is less critical than assessing potential exposure to HIV.